Digital Twin: Harmonix is a rhythm roguelike about diving into complex biological simulations, collecting valuable information, and using it to create life. At its core, the game is built around instrument-style rhythm gameplay. Notes arrive in complex patterns, and your job is to read, react, and perform using a unique 12-button control scheme. Each simulation is a playable biological environment, turning living systems into rhythm charts filled with color, motion, and strange organic energy. Every run gives you a chance to gather data and recover DNA from the environment. The better you perform, the more you can bring back to the lab. Between runs, use the DNA you have collected to assemble new creatures. Experiment with different genetic combinations, discover new traits, and create organisms that change how you approach future simulations. Part rhythm game, part roguelike progression system, and part psychedelic biology experiment, Digital Twin: Harmonix is about mastering the music of living systems and using what you find to create something new.